研究顯示雙酚A會影響女性卵巢功能

2011-3-28 10:41| 發(fā)布者: jieming| 查看: 947| 評論: 2|來自: 食品伙伴網(wǎng)

摘要: 據(jù)外媒報道，一篇最新的研究顯示，高劑量的雙酚A可能會影響人體的生殖功能，并且在其影響下，女性可能會染上多囊卵巢綜合癥(PCOS)。

　　據(jù)外媒報道，一篇最新的研究顯示，高劑量的雙酚A可能會影響人體的生殖功能，并且在其影響下，女性可能會染上多囊卵巢綜合癥(PCOS)。

　　該研究發(fā)表于《臨床內(nèi)分泌學和代謝雜志》，對比了患有多囊卵巢綜合癥組的71名女性與空白組的100名女性中的雙酚A與激素的水平。結果顯示，患多囊卵巢綜合癥的女性體內(nèi)雙酚A的水平顯著高于排卵功能正常的女性，并且高水平的雙酚A與多囊卵巢綜合癥的發(fā)病率呈現(xiàn)高度的相關性。對兩組女性而言，雙酚A水平的提高與激素睪酮以及胰島素抗性的提高相關聯(lián)。

　　該研究的作者表示，雙酚A是一種強有力的內(nèi)分泌干擾物質(zhì)，并且有研究表明卵巢對高劑量的雙酚A很敏感，對于體弱、性腺機能不良者而言，受雙酚A影響可能會導致多囊卵巢綜合癥，這已被小白鼠實驗所證明。

　　本文來源：食品伙伴網(wǎng)

　　原文如下：

　　Scientists show BPA exposure can affect ovary function in women

　　New research has indicated that high exposure to bisphenol A (BPA) may affect reproductive function in humans and lead to polycystic ovary syndrome (PCOS) in women pre-disposed to the condition.

　　The study, published in the Journal of Clinical Endocrinology and Metabolism, compared the levels of BPA and hormones in 71 women with PCOS with those of 100 women without the condition. The results showed that levels of BPA were significantly higher in women with PCOS than those with normal ovulation patterns, and that there was a strong association between high levels of BPA and the occurrence of PCOS. Increased BPA levels also correlated with increased levels of the hormone testosterone and insulin resistance in both groups of women.

　　“BPA is a potent endocrine disrupting chemical, and it has been shown that the ovary is sensitive to increased BPA exposure,” says Evanthia Diamanti-Kandarakis, lead researcher based at the Medical School University of Athens.“In susceptible, dysfunctional gonads, BPA exposure may lead to subsequent PCOS development, as experiments in rats have already shown.”